Here's the stuff I've been listening to in my car lately. It's very geeky. Beware.

 

Rick Rashid - From the Labs at Microsoft Research - some very cool stuff.

Trent Henry - Enterprise Security Architecture  kinda of "heavy" but some good stuff in there.

Peter Norvig - Inside Google -  need I say more? Good stuff coming from Google Labs

David Fogel - Accelerating Problem Solving - some amazing talk about machine learning algorithms

Paul Graham on Business and Open Source  very insightful

Ray Kurzweil - "When Humans Transcend Biology" a totally futuristic talk, with lots of interesting questions to think about

LugRadio - Funny show about Linux, but very very funny. What DotNetRocks *used* to be.