We just released Typemock Isolator 4.3 (here is the blog post with details). It's an awesome product but I envy the speed and ease with which oren can change his syntax (it's nice to work alone!) . I can tell you that the next version of Isolator is going to have a new syntax that is more towards the Arrange-act-assert meme (but you could still use the old one if you wanted to) plus lots of cool goodies.

the new version has full support for Ivonna (for ASP.NET webform testing in process) and we have removed .NET 1.1 support. Many other things changed are listed here.