I work a lot with visual studio in a virtual machine, and on a mac, the function keys just get in the way of debugging and what not.

I needed a way to quickly enable and disable the mac function keys. Found my solution over here:

Get FastScripts http://www.red-sweater.com/fastscripts/
and one of these AppleScripts depending on your OS version
Leopard:
http://www.mediafire.com/file/uznnoommljk/
Snow Leopard (works on my mountain lion too):
http://www.mediafire.com/file/2eeywh2ejku/